

A skyblock like no other. There is no sifting for resources or growing resources on trees. Instead, you will get all your initial resources through the calculator mod. Later, you will be able to use Mystical Agriculture or travel to different worlds using Advanced Rocketry to get resources. Botania and Astral Sorcery also has ways to generate ores.
This is a progression-based pack. You will need to go through one mod in order to progress to the next one. Custom recipes have been made to achieve this along with the use of custom multi-blocks from Molecular Machinery. However, this isn't meant to be an expert-like pack. The goal is to be challenging but not grindy. Experience with the mods and JEI will help. Not recommended for newcomers.
These are the questlines to help guide you along:
Calculator
Botania
Extra Utilites
Actually Additions
Astral Sorcery
Thermal
Ender IO
Advanced Rocketry
Mekanism
Draconic Evolution
You will also need to progress through the Twilight Forest, which you can only get to by rocket. Finally, there are creative items that are craftable using Avaritia for that end-of-pack feeling.
Elder Sign's Playthrough (Scientific Edition):
[Unmaintained] Inventory Tweaks by JimeoWan
Advanced Rocketry by zmaster587
AE2 Wireless Terminal Library by TheRealp455w0rd
AI Improvements by DarkGuardsman
Applied Energistics 2 by AlgorithmX2
ArchitectureCraft - TridentMC Version by darkevilmac
Armor Toughness Bar by tfarecnim
Bad Wither No Cookie - Reloaded by Kreezxil
Better Advancements by way2muchnoise
Better Builder's Wands by Portablejim
Better Questing - Quest Book by Drethic
Better Questing - Standard Expansion by Funwayguy
Block Drops (JEI Addon) by KidsDontPlay
Botania: Garden of Glass by Vazkii
Botanic Bonsai by LatvianModder
Building Gadgets by Direwolf20
CodeChickenLib 1.8.+ by covers1624
Colytra (Forge) by ThelllusiveC4
Compact Machines by davenonymous
ConnectedTexturesMod by tterrag1098
Cosmetic Armor Reworked by LainMI
Crafting Tweaks by BlaytheNinth
Draconic Evolution brandon3055
Ender IO Endergy by tterrag1098
Ender Storage 1.8.+ by covers1624
Ender Tweaker by Shadows_of_Fire
EverlastingAbilities by kroeser
FancyMenu [Forge] by Keksuccino
Farming for Blockheads by BlaytheNinth
FastFurnace by Shadows_of_Fire
FastWorkbench by Shadows_of_Fire
Fence Jumper by TheRealp455w0rd
Flat Colored Blocks by AlgorithmX2
Forge MultiPart CBE by covers1624
Forgiving Void by BlayTheNinth
Initial Inventory by Jaredlll08
Integrated Crafting by kroeser
Integrated Dynamics by kroeser
Integrated Terminals by kroeser
Just Enough Calculation by towdium
Just Enough Energistics (JEE) by TheRealp455w0rd
Just Enough Items (JEI) by mezz
Just Enough Pattern Banners by Lorexe
Just Enough Resources (JER) by way2muchnoise
Just Enough Throwing in Fluids (JETIF) Lykrast
Karat Garden by MrAmericanMike
Konkrete [Forge] by Keksuccino
Lapis Stays in the Enchanting Table by csb987
Loot Capacitor Tooltips by tfarecnim
ManaVisualizer by ExtraMeteorP
ME Capability Adapter by rfctksSparkle
Mekanism Generators by bradyaidnc
Mob Grinding Utils by vadis365
Mystical Agradditions by BlakeBr0
Mystical Agriculture by BlakeBr0
NetherPortalFix by BlayTheNinth
No Mob Spawning on Trees by oldjunyi
OpenBlocks Elevator by vsngarcia
Overloaded Armor Bar by tfarecnim
p455w0rd's Library by TheRealp455w0rd
Phosphor (Forge) by jellysquid_
Practical Logistics 2 by sonar_sonic
Progressive Bosses by insane96mcp
Project Intelligence by brandon3055
Shadowfacts' Forgelin by ShadowfactsDev
Solar Flux Reborn by Zeitheron
Super Sound Muffler: Revived by Firstnecron
The Twilight Forest by Benimatic
Thermal Cultivation by TeamCoFH
Thermal Foundation by TeamCoFH
Thermal Innovation by TeamCoFH
Tinker's JEI by Possible_triangle
Toast Control by Shadows_of_Fire
Tomb Many Graves 2 by M4thG33k
TombManyGraves 2 API by M4thG33k
TombManyPlugins - Cosmetic Armor Reworked by M4thG33k
Translocators 1.8.+ by covers1624
Unlimited Chisel Works by asiekierka
Void Island Control by Bartz24
Wireless Crafting Terminal by TheRealp455w0rd
xXx_MoreToolMats_xXx (a PlusTiC fork without the evil, and apparently some new bugs idk) by TeamDman
For a more expert-style pack, try Calculator Skies - Scientific Edition.
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