With Ex Nihilo and Ex Compressum, you can create all vanilla and included ores out of nothing. You also can also create numerus, magical gadgets with the power of the plants. With Ender IO you can create machines for almost every use you can think of. There are still more mods in this modpack, but you probally still want to discover somthings by yourself.
So you can build every item without mining that block somewhere in your world and automate everything. This is perfect for Skyblock or similar gamemodes where you can't or don't want to go all around the world to collect the necessery resources.