My friends and I have constructed to run on a lighter spec computer allowing for construction of massive bases and automation through AE2, Create, draconic evolution, and mine colonies with a few other mods so you can make those towns as nice as you like.
There is expanded food and resource farming through farmers delight, butchery, botania, various botany pot mods, mystical agriculture as well as a few create food production mods.
explore in confidence with weapons armor backpacks & magic from create, blood magic, and a few others
and explore new horizons with mod packs such as ad astra, dr who's tardis & more
automation is king and create, AE2, extreme reactors, flux networks and a few expansions for each allow you to harvest store move and create even more.

