While some recipes seem overly expensive, you can fortune ores to get nearly double with Fortune III. There are ways to get much more than that
All the ores (in the overworld)
The vast majority of machines, if not all of them, have custom recipes fitting for where they are in the progression tree. This is clearly a late game one
Makes circuits and such, cheaper than crafting. Can be upgraded as you progress, from early to end game
For simple machines
Nearly 300 quests, guiding through progression & providing rewards
Most alloy recipes are changed from default to incorporate new minerals
Just black steel, a nether alloy
Here are two different copper chains. With fortune and advanced machines, you can get a very high yield
Used in machine upgrades, and more, upgradium can be upgraded throughout the game to be used in more advanced contexts
First graphite electrodes are made in a simple manner by infusing dust with starlight, changing the crystal structure just enough to be used in the Arc Furnace
Asphalt and tartarite
An elemental alloy, this is used in various late game tech products
Endgame machine. Not saying anything else about it :D
All custom items and fluids