Material Energy^4

Thank you to anyone who still downloads this modpack today.

I've done a massive overhaul to the modpack to fix longstanding bugs and issues.

Mod changes:
Updated most mods that had an update available
The following mods have been replaced with GTNH forks: Not Enough Items, Applied Energistics 2
YAMPST removed
SerializationisBad added
Aura Cascade removed
TrashSlot added (The UI for this slot will be visually distinct and can't be changed, sorry!)
WAILA Harvestability added
HQM Keybind added
Entity Culling Forge/Fabric added
Armor Tooltip added

Quest changes:

Climate Control quest changed to give Gelid Cryotheum Florbs upon completion. Additional repeatable quest added to convert gelid cryotheum into Gelid Cryotheum Florbs.
Nether Star into Compressed Cookies quest removed. (Replaced with a crafting recipe to turn nether stars into compressed cookies at a far better conversion rate)
4 of the 7 post-game quests nerfed to be possible to do in a reasonable amount of time.
Amber Wool quest no longer requires the Lost Souls quest to be completed.

Charcoal Charcoal quest text adjusted. Will now also mention that graphite bars can be crafted into Charcoal Charcoal.
Golden Bag of Holding quest created.
Overworld's End Portal/Deep Dark portal coordinates now listed in a specific quest.
Fixed Redstone Meltdown quest not accepting gelid cryotheum.
Orichalcum shards reward in Orichalcum quest replaced with a reward bag. (The shards were useless)
Typos in Wither Witches quest fixed
Invalid item reward in Meutoite quest replaced with Ender Cores
Empty Reward bag rewards removed

Map changes:
The number of 1k Storage Cells in the Observatory Strongbox has been increased from 4 to 10.
Removed the already-placed Big Button on the starting platform. (It was meant for the player to place)
Hardened Energy Cells in Reactor room have their RF I/O maxed by default.
Erroneous text on Victory Monument Wools fixed.
Sign in Spatial IO room has had some extra helpful text added.
The Biosphere/Miner's Delight/Rotunda chambers have had some Ineffable Glass and Glowstone added in specific spots to tone down the difficulty and to reduce the likelihood of mobs reaching the Observatory entrance.

Duplicate Squid trophy in an item buffer replaced with a reward bag.
Duplicate Snow Golem trophy in an item buffer replaced with a reward bag.
Duplicate Slime Trophy in an item buffer replaced with a reward bag.
Duplicate Ghast trophy in an item buffer replaced with a reward bag.

Pre-placed Travel Anchors adjusted to reduce overlapping text.
Rebuilt a part of the Chemical Lab due to some mod issues, remains ~95% the same.
Observatory AE2 Dense Cable poking out of the ground replaced with Smart Cable.
Observatory Travel Anchor platform lowered to reduce instances of fall damage.
Hole in Rotunda's Wool room fixed.
Nethersphere overall nerfed as a response to the disabling of Ender IO's modification of Wither Skeletons.
Changes includes: Ineffable Glass entrance, Glowstone added in bridge sections to ward off mob spawns, additional fencing to reduce the threat of ranged mobs, number of spawners reduced, spawner spawn frequency drastically reduced. 
Signed added to everything in the Victory Monument room.
Fixed Reflection of Space's no-texture blocks.
Biosphere's lootable Bronze Leggings no longer have the Health Bonus enchant. (It didn't work)
Biosphere's lootable Bronze Chestplate now has Health Bonus III.
Sky Stone chamber housing the Deep Dark Wool no longer has missing glass.
Number of spawners at The Evil Railway cut in half.
Inclusion Chamber^4 missing glass near entrance fixed.
Inclusion Chamber^4 Garden Soil replaced with Fertilized Dirt.

Config/balance changes:
Hunger drains half as fast
Food restores half as much hunger
Hunger regeneration speed raised from 125% to 200%
Intention is to reduce downtime between fights, and have periods of downtime be less frequent
Tinker Tools no longer lose 10% durability on death
Domesticating Animals now only requires 2 generations on average. (Far easier)
Creepers can no longer naturally spawn as Charged Creepers. (Other methods for Charged Creepers to spawn/be made are still possible)
Ender IO's modified Wither Skeletons no longer spawn. (This makes the experience significantly harder, so Nethersphere has been nerfed. This was to resolve a crash.)
Dire Wolves damage reduced from 20 to 16.
Dire Wolf howl chance reduced from 0.5 to 0.1 (reduces audio spam)
Enderminy HP reduced from 40 to 30.
Fallen Knight ranged attack maximum delay increased. (Slightly slower firing speed on average)
Holoinventory update frequency 1 seconds > 0.1 seconds.
Chemical Synthesis Machine power costs reduced by 20%.
Skeletons no longer spawn from your gravestone.
# of Cookies required to craft the Torcherino divided by 9.
Radioactive elements have a dramatically increased half-life decay time.
Some other config changes that I likely forgot.

Bug fixes/miscellaneous changes:
Resolved a crash related to Skeletons turning into Wither Skeletons in Witch Water.
Fixed Dire Wolf spawners in Keeby's Idea Machine
Quest Book can now be opened with a bindable hotkey.
Certain Blaze spawners are no longer able to spawn Blazes up to 800 blocks away.
Empty Fluid Drum/Bedrockium Drum reward bag rewards removed/replaced.
10 Resonant Energy Cell reward from Epic reward bag fixed so that the Energy Cells are full.
Fixed/updated several other reward bag rewards.