After several false starts, I finally managed to get an update finished that I'm happy with. Most of the issues were caused by major problems within GTCE and Gregic Additions which eventually got sorted out.
There's still one major problem involving CEU/CEF, which is that you can't click to open them. They function fine if you use item transfer conduits or similar mechanisms, its just that the user interface for them won't come up. This isn't progression blocking since there's a workaround, but I'll continue to try to get a response back from the CEU mod dev.
All circuits and all the quests involving them have been reworked. The quests are only complete up until HV tier, but next update should finish off the higher tiers. There are no major balance changes and no ore gen changes, so you should be fine to continue on your current playthroughs.